Drug design: Clues for drugging the ‘undruggable’
Most FDA-approved small molecule drugs inhibit enzymes — biology’s protein machines that catalyze chemical reactions. However, many proteins in biology […]
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Most FDA-approved small molecule drugs inhibit enzymes — biology’s protein machines that catalyze chemical reactions. However, many proteins in biology […] A study in mice has shown that it may be possible to detect the early signs of atherosclerosis, which leads […] Think of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that […] A type of ‘supercharged’ immune cell could be mass-produced to help fight cancer. The researchers behind the early-stage finding, from […] Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not […] Babies exposed to higher levels of organochlorine compounds in the womb go on to have worse lung function in childhood, […] Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which […] Children’s growth in the first three years of life affects the development of their lungs and the risk of asthma […] The maintenance workers of the vascular system, pericyte cells envelop the surface of blood vessels, supporting their stability, growth and […] University of Toronto researchers have uncovered why some cancers grow faster than others. The team led by Liliana Attisano, Professor […]
Drug design: Clues for drugging the ‘undruggable’
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